Most leg press machines provide movement in a straight line. With straight line movement there is more shearing force at the end point of the movement, and if one locks out at the end point there is greater potential for hyper-extending the knee. As an example see here (warning graphic). At Austin Fitness Trainers and at New Orleans Fitness Trainers we use MedX equipment. The MedX leg press provides an arcing range of motion similar to the rotation of the knee, and it can be set so that there is no locking out at the end point.
From this article, Researchers find stronger links between diabetes and Alzheimer's comes this quote:
“Their study, using mice, found that elevated glucose in the blood – a primary consequence of diabetes -- can rapidly increase levels of amyloid beta, which shows up in brain plaques in Alzheimer’s patients. The buildup of these plaques is believed to be what brings on the memory loss that Alzheimer’s causes in the brain.”
“If the mice did not have the amyloid plaques in the brains, doubling their blood glucose levels increased amyloid beta levels in the brain by 20%. When the scientists repeated the experiment in older mice that already had developed brain plaques, amyloid beta levels rose by 40%”
After a high intensity strength training workout you will be breathing hard. This video was taken three minutes after a workout, so that I could get some of my wind back and have my pulse come down a bit. EPOC, Essessive Post-Exercise Oxygen Consumption is high after aerobic exercise, higher still after a strength training workout, and highest after a high intensity strength training workout. A higher level of EPOC means more calories burned. With a high intensity strength training workout, besides getting stronger, you will positively affect your cardiovascular system, lower your sugar, and and burn calories long after the workout is over.